Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | RECQL | P46063 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048092 | 0.86 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Dioncoquinone B SCHEMBL3401149 | 0.85 | MEN1 (0.60) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL18048114 | 0.84 | MAPT (0.52) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL13752255 | 0.79 | STAT3 (0.37) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL30004289 | 0.77 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL5810491 | 0.77 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Droserone SCHEMBL5858407 | 0.77 | MAOA (0.67) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Droserone SCHEMBL30003199 | 0.77 | MAOA (0.67) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3265542 | 0.77 | MAPT (0.67) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3431641 | 0.70 | RAB9A (0.59) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | NCL, SYNCRIP, MYC | MAPT 4212/4885MEN1 2620/4885KMT2A 3017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.