Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.58 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753112 | 0.88 | POLB (0.59) | DDR1SORT1ALDH1A1POLBEPHX2 | |
| SCHEMBL13752999 | 0.88 | PPARD (0.50) | DDR1KDM4EHTTRXFP1 | |
| SCHEMBL13753088 | 0.84 | CES2 (0.60) | DDR1SORT1ALDH1A1POLBTMPRSS4 | |
| SCHEMBL4817422 | 0.84 | DDR1 (0.52) | DDR1SORT1ALDH1A1TMPRSS4TRPV1 | |
| SCHEMBL7363177 | 0.83 | MLYCD (0.54) | DDR1ALDH1A1POLBEPHX2HPGD | |
| SCHEMBL21841270 | 0.83 | DDR1 (0.51) | DDR1SORT1TMPRSS4TRPV1MRGPRX4 | |
| SCHEMBL13754025 | 0.83 | CCR2 (0.52) | ALDH1A1KDM4EHPGD | |
| SCHEMBL13753890 | 0.83 | JAK2 (0.57) | DDR1MRGPRX4HPGDLMNA | |
| SCHEMBL14214021 | 0.82 | KDM4E (0.53) | DDR1SORT1ALDH1A1POLBTMPRSS4 | |
| SCHEMBL13753082 | 0.81 | CES2 (0.60) | SORT1ALDH1A1POLBMRGPRX4CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7390830-B1 | Remedies or prophylactics for diseases in association with chemokines | TEIJIN LIMITED (JP) | 2008-06-24 | — | — | US | disclosed |