Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753508 | 0.86 | ALDH1A1 (0.60) | HPGDTSHRSMN1; SMN2NPC1TP53 | |
| SCHEMBL13753516 | 0.85 | HSD11B1 (0.55) | HPGDGAAMEN1MAPK1KMT2A | |
| SCHEMBL3887424 | 0.84 | L3MBTL1 (0.57) | HPGDTSHRSMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL15743801 | 0.84 | HCRTR1 (0.53) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL13753514 | 0.84 | KMT2A (0.58) | HPGDGAAMEN1MAPK1KMT2A | |
| SCHEMBL20826492 | 0.84 | KMT2A (0.58) | HPGDGAAMEN1MAPK1KMT2A | |
| SCHEMBL30524747 | 0.83 | SPHK2 (0.58) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL13570365 | 0.83 | SPHK2 (0.58) | HCRTR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL16759939 | 0.83 | HSD11B1 (0.58) | HCRTR1HCRTR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL13753517 | 0.83 | HPGD (0.71) | HPGDSMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |