Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | CCKBR | P32239 | 3/20 | 0.52 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25789777 | 0.83 | DRD2 (0.69) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL19476076 | 0.83 | DRD2 (0.69) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL4915072 | 0.81 | TAS1R3 (0.57) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL29949076 | 0.80 | DRD2 (0.68) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL13753384 | 0.80 | DRD2 (0.68) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL14269102 | 0.80 | PYGL (0.69) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL13753661 | 0.80 | KDM4E (0.72) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL13761405 | 0.78 | DRD2 (0.59) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL6632042 | 0.78 | KDM4E (0.71) | DRD2GAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL13753482 | 0.77 | DRD2 (0.64) | DRD2GAAKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |