Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | GAA | P10253 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL10533129 | 0.95 | LMNA (0.48) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL10713936 | 0.82 | ALDH1A1 (0.59) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL10705372 | 0.82 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL2454782 | 0.81 | AKR1C4 (0.55) | LMNAALDH1A1HSD17B10POLBTHRB | |
| SCHEMBL10533123 | 0.81 | ALDH1A1 (0.59) | LMNAALDH1A1GAAKDM4EHPGD | |
| SCHEMBL2061521 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4EHPGDMAPT | |
| SCHEMBL28057064 | 0.80 | LMNA (0.40) | LMNAALDH1A1HPGDPOLBTHRB | |
| SCHEMBL11651621 | 0.80 | CYP3A4 (0.56) | LMNAALDH1A1GAAHPGDMAPT | |
| SCHEMBL24397792 | 0.79 | LMNA (0.54) | LMNAALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL24397843 | 0.79 | LMNA (0.50) | LMNAALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |