Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | HAT1 | O14929 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057063 | 0.84 | HSP90AB1 (0.43) | LMNAHSP90AB1GPR35FASNHPGD | |
| SCHEMBL28056987 | 0.84 | FLT1 (0.40) | FLT1FLT4KDRGPR35POLB | |
| SCHEMBL12670866 | 0.82 | FLT1 (0.54) | LMNAGRIN1GRIN2AFLT1FLT4 | |
| SCHEMBL13753818 | 0.80 | LMNA (0.51) | LMNAPRKCZHSP90AB1HPGDPOLB | |
| SCHEMBL13753920 | 0.79 | HSP90AB1 (0.44) | LMNAGRIN1GRIN2AHSP90AB1ELANE | |
| SCHEMBL27816654 | 0.77 | AKR1C2 (0.41) | FLT1FLT4KDRGPR35ALDH1A1 | |
| Diethylamine SCHEMBL10533129 | 0.77 | LMNA (0.48) | LMNAPRKCZHSP90AB1HPGDPOLB | |
| SCHEMBL14976373 | 0.75 | ADRA1D (0.34) | FLT1FLT4KDRGPR35P2RX7 | |
| SCHEMBL2696430 | 0.74 | NPC1 (0.44) | P2RX7IRAK4 | |
| SCHEMBL14976051 | 0.74 | FLT1 (0.34) | FLT1FLT4KDRGPR35HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367548-A | Cyan dihalogenation pyrazol amide series compound and preparation method and application thereof | DENG FANGKUN | 2016-03-02 | — | — | CN | disclosed |