Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 14/20 | 0.73 |
| ▸ | YAP1 | P46937 | 1/20 | 0.66 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.66 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268782 | 0.86 | RXFP1 (0.78) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL1774875 | 0.85 | RXFP1 (0.70) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL1776064 | 0.85 | RXFP1 (0.63) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL1775112 | 0.85 | RXFP1 (0.65) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL14853341 | 0.85 | YAP1 (0.77) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL10516305 | 0.84 | RXFP1 (0.80) | RXFP1YAP1TEAD4TEAD2LMNA | |
| SCHEMBL15528884 | 0.84 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL1774632 | 0.84 | RXFP1 (0.60) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12606017 | 0.83 | RXFP1 (0.67) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12851592 | 0.83 | RXFP1 (0.78) | RXFP1YAP1TEAD4TEAD2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |