Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828529 | 0.85 | RAB9A (0.75) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL13753999 | 0.83 | MAPT (0.61) | MAPTMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL13761552 | 0.77 | MAPT (0.48) | MAPTMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL13761496 | 0.77 | TRPV1 (0.51) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL47353 | 0.76 | MMP13 (0.66) | MAPTMEN1KMT2ATSHRGAA | |
| SCHEMBL31396777 | 0.76 | MAPT (0.64) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL23831406 | 0.75 | MAPT (0.64) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL23831221 | 0.75 | GRIK1 (0.61) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL23831412 | 0.75 | RAB9A (0.52) | MAPTMEN1KMT2APKMTSHR | |
| SCHEMBL6765010 | 0.74 | MEN1 (0.60) | MAPTMEN1KMT2APKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |