Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767742 | 0.91 | MAPT (0.64) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6763008 | 0.85 | CXCR2 (0.67) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6763521 | 0.85 | FADS1 (0.64) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6763526 | 0.85 | MAPT (0.77) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6760893 | 0.85 | ALDH1A1 (0.60) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6760907 | 0.85 | DDX3X (0.59) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL4356025 | 0.84 | TRPV1 (0.70) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL1463349 | 0.81 | GSK3A (0.66) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL6764102 | 0.81 | CXCR1 (0.62) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL6763519 | 0.81 | MEN1 (0.70) | MEN1KMT2AMAPTPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | claimed |
| US-20040063742-A1 | Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity | NEUROSEARCH A/S (DK) | 2004-04-01 | — | — | US | disclosed |