SCHEMBL13754170

SCHEMBL13754170

CCCCCCCCCC(C)COC(OCC(C)CCCCCCCCC)C(=O)c1ccc(NC(=O)C(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.42
S1PR1 P21453 3/20 0.40
S1PR3 Q99500 3/20 0.40
LMNA P02545 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SLC2A1 P11166 1/20 0.38
BDKRB2 P30411 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PRSS1 P07477 1/20 0.37
CTSG P08311 1/20 0.37
CTRB1 P17538 1/20 0.37
CMA1 P23946 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SPHK1 Q9NYA1 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.36
S1PR4 O95977 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457275 0.78 TAS1R3 (0.42) LMNASMN1; SMN2PRSS1CTSGCTRB1
SCHEMBL13754169 0.77 NR1H4 (0.45) L3MBTL1LMNASMN1; SMN2MAPT
SCHEMBL13754149 0.77 TP53 (0.50) L3MBTL1LMNASLC2A1SMN1; SMN2MEN1
SCHEMBL4456428 0.74 TP53 (0.47) SLC2A1
SCHEMBL4457011 0.74 SLC6A4 (0.47)
SCHEMBL13754161 0.71 TAS1R3 (0.51) RAB9AHTTSMN1; SMN2MEN1KMT2A
SCHEMBL28701516 0.69 SPHK1 (0.63) L3MBTL1S1PR1NPC1RAB9ASPHK1
SCHEMBL29037524 0.69 SPHK1 (0.63) L3MBTL1S1PR1NPC1RAB9ASPHK1
SCHEMBL15503323 0.69 SPHK1 (0.63) L3MBTL1S1PR1NPC1RAB9ASPHK1
SCHEMBL28411160 0.67 MAPT (0.58) LMNANPC1RAB9ASMN1; SMN2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed
US-7572938-B2 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2009-08-11 US disclosed