Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456428 | 0.92 | TP53 (0.47) | TP53TSHRPLA2G4BRARBPPARG | |
| SCHEMBL13754150 | 0.83 | SMN1; SMN2 (0.42) | TP53TSHRPLA2G4BMEN1LMNA | |
| SCHEMBL4457275 | 0.81 | TAS1R3 (0.42) | TP53TSHRPLA2G4BLMNAMAPT | |
| SCHEMBL4456979 | 0.78 | PPARG (0.47) | TP53TSHRPLA2G4BRARBPPARG | |
| SCHEMBL4457011 | 0.77 | SLC6A4 (0.47) | TSHRPLA2G4BMAPK1 | |
| SCHEMBL13754170 | 0.77 | L3MBTL1 (0.42) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10616413 | 0.77 | TP53 (0.75) | TP53TSHRPLA2G4BMAPK1RARB | |
| SCHEMBL10616405 | 0.77 | TP53 (0.75) | TP53TSHRPLA2G4BMAPK1RARB | |
| SCHEMBL13754141 | 0.76 | NR4A2 (0.44) | MEN1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL19130711 | 0.76 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | disclosed |