Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457011 | 0.78 | SLC6A4 (0.47) | TSHR | |
| SCHEMBL4457275 | 0.75 | TAS1R3 (0.42) | TAS1R3TAS1R1TSHRMAPTALDH1A1 | |
| SCHEMBL27803328 | 0.75 | TAS1R3 (0.48) | TAS1R3TAS1R1TSHRHPGDMAPT | |
| SCHEMBL13754149 | 0.74 | TP53 (0.50) | TSHRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25745529 | 0.74 | TAS1R3 (0.60) | TAS1R3TAS1R1TSHRHPGDALDH1A1 | |
| SCHEMBL4456428 | 0.72 | TP53 (0.47) | TSHR | |
| SCHEMBL11629969 | 0.72 | ALDH1A1 (0.65) | TAS1R3TAS1R1HPGDMAPTALDH1A1 | |
| SCHEMBL16429605 | 0.72 | ALDH1A1 (0.67) | TAS1R3TAS1R1HPGDALDH1A1MEN1 | |
| SCHEMBL15273098 | 0.72 | ALDH1A1 (0.67) | TAS1R3TAS1R1HPGDALDH1A1MEN1 | |
| SCHEMBL13754170 | 0.71 | L3MBTL1 (0.42) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572938-B2 | Precursors for ketones and aldehydes | GIVAUDAN SA (CH) | 2009-08-11 | — | — | US | disclosed |