SCHEMBL13754262

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12560288	0.89	PTGS2 (0.59)	PTGS2CA2MEN1KMT2ARXFP1
	SCHEMBL20866271	0.85	PTGS2 (0.55)	PTGS2CA2TUBB1HTR2AHTR2C
	SCHEMBL88770	0.83	PTGS2 (0.48)	PTGS2MEN1KMT2ARXFP1KDM4E
	SCHEMBL30374	0.80	PTGS2 (1.00)	PTGS2TUBB1HTR2AHTR2CHTR2B
	SCHEMBL3397035	0.80	CA2 (0.43)	PTGS2CA2MEN1KMT2ARXFP1
	SCHEMBL901445	0.78	PTGS2 (0.64)	PTGS2CA2MEN1KMT2AKDM4E
	SCHEMBL8429647	0.78	PTGS2 (0.64)	PTGS2CA2TUBB1HTR2AHTR2C
	SCHEMBL22946267	0.78	PTGS2 (0.46)	PTGS2MEN1KMT2AHTR2AHTR2C
	SCHEMBL13145025	0.78	CA2 (0.41)	PTGS2CA2MEN1KMT2ARXFP1
	SCHEMBL27685436	0.78	PTGS2 (0.64)	PTGS2CA2TUBB1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.