Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.63 |
| ▸ | MMP2 | P08253 | 7/20 | 0.63 |
| ▸ | MMP9 | P14780 | 7/20 | 0.63 |
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449565 | 0.87 | MMP1 (0.71) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL28449561 | 0.87 | MMP1 (0.71) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL10492396 | 0.81 | MMP1 (0.77) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL10492394 | 0.81 | MMP1 (0.77) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL6885772 | 0.78 | ALDH1A1 (0.79) | MAPTSMN1; SMN2KMT2ALMNAGAA | |
| SCHEMBL6885764 | 0.78 | ALDH1A1 (0.79) | MAPTSMN1; SMN2KMT2ALMNAGAA | |
| N-O-Tolylcinnamamide SCHEMBL15902545 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-P-Tolylcinnamamide SCHEMBL1603280 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-O-Tolylcinnamamide SCHEMBL2593754 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-O-Tolylcinnamamide SCHEMBL2593756 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575926-B1 | Method of identification of compounds effective against suppressed cancer cells | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2009-08-18 | — | — | US | disclosed |