Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13332852 | 0.98 | SLC6A4 (0.70) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL13755345 | 0.94 | SLC6A4 (0.65) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL12263179 | 0.90 | SLC6A4 (0.58) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL3517010 | 0.85 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL3516240 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL3519813 | 0.82 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL16298324 | 0.79 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3519928 | 0.79 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL10623441 | 0.78 | SLC6A4 (0.89) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL3519750 | 0.78 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023865-B2 | Compounds that are ERK inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140296203-A1 | NOVEL COMPOUNDS THAT ARE ERK INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| US-20090215779-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296203-A1 | NOVEL COMPOUNDS THAT ARE ERK INHIBITORS | MAPK1, MAPK10, MAP3K1 | SLC6A4 4432/4885SLC6A3 4161/4885CYP3A4 2691/4885 |
| US-20090215779-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT2, GPR119, DGAT1 | SLC6A4 1186/4885SLC6A3 372/4885CYP3A4 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.