Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375575 | 0.86 | KDM4E (0.48) | GPR84KDM4EMEN1KMT2ANQO2 | |
| SCHEMBL13010579 | 0.85 | GPR84 (0.36) | GSTP1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL20127333 | 0.84 | ABCG2 (0.41) | GSTP1GPR84MEN1KMT2ACYP1B1 | |
| SCHEMBL13010585 | 0.84 | PIM1 (0.41) | GSTP1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL25784829 | 0.83 | GPR84 (0.37) | GSTP1GPR84KDM4EMEN1KMT2A | |
| SCHEMBL20127738 | 0.83 | ABCG2 (0.40) | GSTP1GPR84MEN1KMT2AESR1 | |
| SCHEMBL16067878 | 0.83 | CDK4 (0.39) | KDM4EMEN1KMT2ANQO2CYP1B1 | |
| SCHEMBL16067579 | 0.83 | CDK4 (0.38) | KDM4EMEN1KMT2ANQO2CYP1B1 | |
| SCHEMBL27961488 | 0.83 | GPR84 (0.47) | GSTP1GPR84MEN1KMT2AHDAC4 | |
| SCHEMBL20127295 | 0.82 | ABCG2 (0.40) | KDM4EMEN1KMT2ACYP1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006503-B2 | Organic electroluminescence devices containing substituted benzo[C]phenanthrenes | MERCK PATENT GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| CN-102282234-B | Material for organic electroluminescent device | MERCK PATENT GMBH | 2014-07-30 | — | — | CN | disclosed |
| US-8710284-B2 | Materials for organic electroluminescent devices containing substituted 10-benzo[c]phenanthrenes | MERCK PATENT GMBH (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20140114076-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| CN-102282234-A | Material for organic electroluminescent device | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110288292-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010083869-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288292-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | DDT, DDC, BMI1 | GSTP1 530/4885GPR84 3695/4885KDM4E 1250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.