Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 6/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.44 |
| ▸ | SI | P14410 | 4/20 | 0.44 |
| ▸ | AMY2A | P04746 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17992017 | 0.94 | AMY2A (0.48) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL13073700 | 0.89 | LGALS8 (0.44) | LGALS8AMY2ALGALS3LGALS4GAA | |
| SCHEMBL1097727 | 0.87 | LGALS3 (0.46) | LGALS8AMY2ALGALS3LGALS4GAA | |
| SCHEMBL20374903 | 0.86 | LGALS8 (0.47) | LGALS8LGALS3LGALS4GAA | |
| SCHEMBL7151072 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL21842956 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL12787301 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL7155639 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL10005644 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 | |
| SCHEMBL18068840 | 0.85 | LGALS8 (0.51) | LGALS8MGAMSIAMY2ALGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627061-B1 | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) | SIRNA THERAPEUTICS INC (US) | 2009-08-12 | — | — | EP | disclosed |