Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751088 | 0.87 | CDC25A (0.41) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL14434585 | 0.85 | CDC25A (0.42) | MAPK1HDAC1HDAC6HDAC3HDAC11 | |
| SCHEMBL13751093 | 0.82 | HDAC1 (0.46) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL14434564 | 0.81 | HDAC1 (0.45) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL16117997 | 0.80 | ALDH1A1 (0.56) | HPGDHSD17B10HDAC1HDAC6HDAC3 | |
| SCHEMBL13751092 | 0.79 | HDAC1 (0.41) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL5379056 | 0.79 | ALDH1A1 (0.45) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL14434588 | 0.79 | HDAC1 (0.45) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL13751087 | 0.79 | HDAC1 (0.42) | MAPK1HPGDHSD17B10HDAC1HDAC6 | |
| SCHEMBL16118001 | 0.78 | TSHR (0.50) | HPGDALDH1A1LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214460-A9 | Composition Comprising a Monomer Compound Exhibiting an Optical Property, Method Making Use of Said Composition, a Monomer Compound and a Polymer Containing Said Monomer Compound and the Use Thereof | L'OREAL S.A. (FR) | 2009-08-27 | — | — | US | disclosed |
| US-20080226581-A1 | Composition Comprising a Monomer Compound Exhibiting an Optical Property, Method Making Use of Said Composition, a Monomer Compound and a Polymer Containing Said Monomer Compound and the Use Thereof | L'OREAL S.A. (FR) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226581-A1 | Composition Comprising a Monomer Compound Exhibiting an Optical Property, Method Making Use of Said Composition, a Monomer Compound and a Polymer Containing Said Monomer Compound and the Use Thereof | KRT18, MITF, CUTA | MAPK1 3022/4885HPGD 1836/4885HSD17B10 3831/4885 |
| US-20090214460-A9 | Composition Comprising a Monomer Compound Exhibiting an Optical Property, Method Making Use of Said Composition, a Monomer Compound and a Polymer Containing Said Monomer Compound and the Use Thereof | KRT18, MITF, CUTA | MAPK1 3022/4885HPGD 1836/4885HSD17B10 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.