Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22673245 | 0.90 | CACNA1H (0.37) | ALDH1A1TDP1SMN1; SMN2SIGMAR1KDM4E | |
| SCHEMBL20482154 | 0.84 | CACNA1H (0.39) | ALDH1A1TDP1SMN1; SMN2SIGMAR1KDM4E | |
| SCHEMBL24356046 | 0.84 | CACNA1H (0.39) | ALDH1A1TDP1SMN1; SMN2SIGMAR1KDM4E | |
| SCHEMBL13445999 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2SIGMAR1MEN1 | |
| SCHEMBL17093968 | 0.83 | SIGMAR1 (0.47) | ALDH1A1SMN1; SMN2SIGMAR1KDM4ELMNA | |
| SCHEMBL20240907 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1SMN1; SMN2SIGMAR1MEN1 | |
| SCHEMBL2282322 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TDP1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL70778 | 0.80 | TSHR (0.46) | ALDH1A1TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL12379861 | 0.80 | TSHR (0.46) | ALDH1A1TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL1133592 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8545813-B2 | Pre-templated macromolecular architectures with multiple Gd(III) complexes and methods of use as MRI contrast agents | NORTHWESTERN UNIVERSITY (US) | 2013-10-01 | — | — | US | disclosed |
| US-20090196829-A1 | MRI CONTRAST AGENTS AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090196829-A1 | MRI CONTRAST AGENTS AND RELATED METHODS OF USE | MAG, AQP4, LPXN | ALDH1A1 3871/4885TDP1 2300/4885SMN1; SMN2 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.