Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24356046 | 1.00 | CACNA1H (0.39) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL22673245 | 0.96 | CACNA1H (0.37) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL7130844 | 0.84 | ALDH1A1 (0.53) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL13759079 | 0.84 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8183645 | 0.84 | SIGMAR1 (0.43) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL14289006 | 0.83 | SIGMAR1 (0.42) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL18291886 | 0.82 | SIGMAR1 (0.41) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 | |
| SCHEMBL21946338 | 0.81 | BCHE (0.38) | CACNA1HALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15693173 | 0.81 | BCHE (0.38) | CACNA1HALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7157890 | 0.81 | SIGMAR1 (0.40) | CACNA1HSIGMAR1ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226231-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE (FR) | 2023-07-20 | — | — | US | disclosed |
| EP-4168054-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | Universite d'Aix Marseille (FR) | 2023-04-26 | — | — | EP | disclosed |
| WO-2021255282-A1 | CONJUGATED AND LABELLED APELIN, PREPARATION AND USES THEREOF | UNIVERSITE D'AIX MARSEILLE (FR) | 2021-12-23 | — | — | WO | disclosed |
| WO-2018154034-A1 | RADIOLABELED SOLUBLE CD146, PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-08-30 | — | — | WO | disclosed |