Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267140 | 0.81 | ALDH1A1 (0.59) | HTTTSHRKMT2AMEN1POLB | |
| SCHEMBL31483721 | 0.79 | HTT (0.64) | HTTTSHRKMT2AHPGDNAAA | |
| SCHEMBL26417076 | 0.79 | HTT (0.64) | HTTTSHRKMT2AHPGDNAAA | |
| SCHEMBL27452233 | 0.78 | RAB9A (0.68) | HTTTSHRKMT2AMEN1POLB | |
| SCHEMBL28810852 | 0.77 | RAB9A (0.61) | HTTTSHRKMT2AMEN1POLB | |
| SCHEMBL9549306 | 0.76 | MLYCD (0.49) | HTTTSHRKMT2AMEN1POLB | |
| SCHEMBL13754121 | 0.76 | HPGD (0.50) | HTTTSHRKMT2AMEN1TAS1R3 | |
| SCHEMBL11823698 | 0.76 | MEN1 (0.83) | HTTTSHRKMT2AMEN1POLB | |
| SCHEMBL22060734 | 0.74 | NPC1 (0.57) | TSHRKMT2AMEN1POLBNPC1 | |
| SCHEMBL5332053 | 0.74 | MLYCD (0.68) | HTTTSHRKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |