Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13754271 | 1.00 | RAB9A (0.64) | RAB9ASMN1; SMN2HPGDALDH1A1GPR132 | |
| SCHEMBL13753371 | 0.83 | ALDH1A1 (0.71) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL5529012 | 0.82 | CTSL (0.76) | RAB9ASMN1; SMN2HPGDALDH1A1GPR132 | |
| SCHEMBL13753583 | 0.80 | ALDH1A1 (0.65) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13753830 | 0.79 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13754272 | 0.79 | ALDH1A1 (0.74) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13754119 | 0.79 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13753779 | 0.79 | ALDH1A1 (0.64) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13761468 | 0.79 | ALDH1A1 (0.74) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 | |
| SCHEMBL13753676 | 0.78 | HPGD (0.66) | RAB9ASMN1; SMN2HPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |