Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764317 | 0.84 | CHEK1 (0.47) | PIK3CDCNR1CNR2ALOX5ANO1 | |
| SCHEMBL13764318 | 0.78 | CHEK1 (0.49) | PIK3CDCNR1CNR2ALOX5ANO1 | |
| SCHEMBL13776782 | 0.75 | CHEK1 (0.49) | PIK3CDCNR1CNR2ALOX5ANO1 | |
| SCHEMBL26447571 | 0.74 | GPR119 (0.45) | PIK3CDHDAC4HDAC6USP30JAK3 | |
| SCHEMBL16797316 | 0.74 | MAPK1 (0.50) | PIK3CDCNR1CNR2HDAC4HDAC6 | |
| SCHEMBL30034326 | 0.74 | MAPK1 (0.50) | PIK3CDCNR1CNR2HDAC4HDAC6 | |
| SCHEMBL13764319 | 0.73 | CNR1 (0.47) | PIK3CDCNR1CNR2ALOX5ANO1 | |
| SCHEMBL6523004 | 0.72 | IGF1R (0.45) | PIK3CDCNR1CNR2ANO1HDAC4 | |
| SCHEMBL20155254 | 0.72 | IGF1R (0.45) | PIK3CDCNR1CNR2ANO1HDAC4 | |
| SCHEMBL6523000 | 0.72 | IGF1R (0.45) | PIK3CDCNR1CNR2ANO1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557104-B2 | Imidazopyrazines as protein kinase inhibitors | SCHERING CORPORATION (US) | 2009-07-07 | — | — | US | disclosed |
| US-20080027063-A1 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027063-A1 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | CHEK1, CHEK2, CDKN1A | PIK3CD 283/4885CNR1 2724/4885CNR2 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.