Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679321 | 0.88 | F10 (0.65) | F10RAB9A | |
| SCHEMBL1379173 | 0.87 | F10 (0.57) | F10CNR1MAPTALDH1A1KMT2A | |
| SCHEMBL6179994 | 0.87 | F10 (0.59) | F10CNR1 | |
| SCHEMBL1380646 | 0.85 | F10 (0.62) | F10MAPT | |
| SCHEMBL6182831 | 0.85 | F10 (0.59) | F10MAPTNPC1 | |
| SCHEMBL1380603 | 0.85 | F10 (0.59) | F10ALDH1A1 | |
| SCHEMBL1381539 | 0.85 | F10 (0.59) | F10ALDH1A1KMT2A | |
| SCHEMBL1382884 | 0.84 | F10 (0.55) | F10CNR1MAPTALDH1A1KDM4E | |
| SCHEMBL5873331 | 0.83 | F10 (0.55) | F10ALDH1A1NPC1TP53TSHR | |
| SCHEMBL1376448 | 0.82 | RAB9A (0.52) | F10CNR1CNR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558247-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |