SCHEMBL13764796

SCHEMBL13764796

C=CCOC(=O)C(N1C(=O)[C@H]([C@@H](C)O[Si](C)(C)C(C)(C)C)[C@H]1[C@@H](C)C(=O)OC(=O)c1ccc(OC)cc1)=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ELANE P08246 1/20 0.31
OPRD1 P41143 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3871262 1.00 ADRB2 (0.31) ADRB2ADRB1ADRB3ALDH1A1ELANE
SCHEMBL13764797 0.91 ELANE (0.30) ALDH1A1ELANE
SCHEMBL3871557 0.91 ELANE (0.30) ALDH1A1ELANE
SCHEMBL13764799 0.90 ELANE (0.31) ELANE
SCHEMBL3873049 0.90 ELANE (0.31) ELANE
SCHEMBL6892042 0.88 FAAH (0.33) ELANEFAAH
SCHEMBL13764795 0.88 FAAH (0.33) ELANEFAAH
SCHEMBL3873801 0.88 FAAH (0.33) ELANEFAAH
SCHEMBL6892231 0.87 ELANE (0.33) ELANEFAAH
SCHEMBL13946276 0.87 ELANE (0.33) ELANEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563901-B2 Intermediates of 2-substituted carbapenem derivatives and process for production thereof MEIJI SEIKA KAISHA, LTD. (JP) 2009-07-21 US disclosed
US-7524951-B2 Intermediates of 2-substituted carbapenem derivatives and process for production thereof MEIJI SEIKA KAISHA, LTD. (JP) 2009-04-28 US disclosed
US-20090082571-A1 Intermediates of 2-substituted carbapenem derivatives and process for production thereof SASAKI TOSHIRO 2009-03-26 US disclosed
US-20080167475-A1 Intermediates of 2-substituted carbapenem derivatives and process for production thereof SASAKI TOSHIRO 2008-07-10 US disclosed
US-20080076917-A1 Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof MEIJI SEIKA KAISHA, LTD. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167475-A1 Intermediates of 2-substituted carbapenem derivatives and process for production thereof MGAM, G6PD, COASY ADRB2 2222/4885ADRB1 1570/4885ADRB3 3028/4885
US-20080076917-A1 Intermediates of 2-Substituted Carbapenem Derivatives and Process for Production Thereof MGAM, G6PD, COASY ADRB2 2222/4885ADRB1 1570/4885ADRB3 3028/4885
US-20090082571-A1 Intermediates of 2-substituted carbapenem derivatives and process for production thereof MGAM, G6PD, COASY ADRB2 2222/4885ADRB1 1570/4885ADRB3 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.