Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631326 | 0.79 | KDM4E (0.53) | ALDH1A1HTTMAPTKDM4EHSD17B10 | |
| SCHEMBL12075071 | 0.79 | MAPT (0.67) | ALDH1A1HTTMAPTKDM4EHSD17B10 | |
| SCHEMBL12057593 | 0.75 | KIF11 (0.53) | KIF11ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL12057618 | 0.75 | KIF11 (0.53) | KIF11ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL12057611 | 0.75 | KIF11 (0.53) | KIF11ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL21603687 | 0.66 | CNR2 (0.71) | ALDH1A1MAPTKDM4EHSD17B10FLT3 | |
| SCHEMBL3684643 | 0.66 | ALDH1A1 (0.74) | KIF11ABCC1ALDH1A1HTTMAPT | |
| SCHEMBL21603765 | 0.66 | CNR2 (0.77) | ALDH1A1MAPTKDM4EHSD17B10FLT3 | |
| SCHEMBL21604028 | 0.66 | CNR2 (0.70) | ALDH1A1MAPTKDM4EHSD17B10FLT3 | |
| SCHEMBL10827185 | 0.65 | PRCP (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009087564-A1 | PROLINE ANALOGS AS LIGANDS FOR CANNABINOID RECEPTORS FOR THE TREATMENT OF PAIN | PURDUE PHARMA L.P. (DE) | 2009-07-16 | — | — | WO | disclosed |