Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | DCK | P27707 | 8/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529654 | 0.87 | RXRA (0.45) | RXRAGRIN1GRIN2BHDAC1HDAC8 | |
| SCHEMBL13530230 | 0.85 | RXRA (0.44) | RXRAGRIN1GRIN2BHDAC1HDAC8 | |
| SCHEMBL14730552 | 0.84 | RXRA (0.40) | RXRAGRIN1GRIN2BHDAC1HDAC8 | |
| SCHEMBL13530231 | 0.83 | RXRA (0.45) | RXRAGRIN1GRIN2BHDAC1HDAC6 | |
| SCHEMBL13529535 | 0.83 | RXRA (0.43) | RXRAGRIN1GRIN2BHDAC1HDAC8 | |
| SCHEMBL13529906 | 0.83 | RXRA (0.46) | RXRAGRIN1GRIN2B | |
| SCHEMBL13764973 | 0.82 | RXRA (0.42) | RXRAGRIN1GRIN2BHDAC1HDAC8 | |
| SCHEMBL13765103 | 0.82 | MAOB (0.40) | RXRAGRIN1GRIN2BDCKMAOB | |
| SCHEMBL13529629 | 0.82 | MAOB (0.52) | MAOB | |
| SCHEMBL13530393 | 0.81 | DHFR (0.43) | RXRAGRIN1GRIN2BDCKMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094442-A2 | 5-FLUORO PYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-07-30 | — | — | WO | disclosed |