Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MGMT | P16455 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DCK | P27707 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530230 | 0.92 | RXRA (0.44) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL318524 | 0.88 | MAOB (0.47) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL29366119 | 0.88 | MAOB (0.47) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL13529747 | 0.86 | RXRA (0.41) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL13530393 | 0.85 | DHFR (0.43) | RXRAGRIN1GRIN2BMAOBMPO | |
| SCHEMBL318183 | 0.85 | MPO (0.43) | RXRAGRIN1GRIN2BMGMTMPO | |
| SCHEMBL29350507 | 0.85 | MPO (0.43) | RXRAGRIN1GRIN2BMGMTMPO | |
| SCHEMBL13530333 | 0.85 | RXRA (0.40) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL19510197 | 0.85 | RXRA (0.40) | RXRAGRIN1GRIN2BMGMTMAOB | |
| SCHEMBL13529576 | 0.85 | RXRA (0.40) | RXRAGRIN1GRIN2BMGMTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562166-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2562161-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |