SCHEMBL13765154

SCHEMBL13765154

C[Si](C)(C)c1ccc(-c2cccc([Si](C)(C)C)c2)nc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.43
HSD17B2 P37059 2/20 0.43
TRPV3 Q8NET8 2/20 0.40
KDM1A O60341 6/20 0.38
ACHE P22303 1/20 0.38
HPGDS O60760 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2A6 P11509 1/20 0.36
MAOB P27338 2/20 0.35
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
LDHA P00338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31754774 1.00 HSD17B1 (0.43) HSD17B1HSD17B2TRPV3KDM1AACHE
SCHEMBL24134487 0.89 HSD17B1 (0.38) HSD17B1HSD17B2TRPV3KDM1AHPGDS
SCHEMBL4906150 0.87 HSD17B1 (0.59) HSD17B1HSD17B2TRPV3KDM1AHPGDS
SCHEMBL16405288 0.86 HSD17B1 (0.45) HSD17B1HSD17B2KDM1ACYP3A4IDO1
SCHEMBL18069588 0.86 CYP3A4 (0.53) HSD17B1HSD17B2TRPV3KDM1ACYP3A4
SCHEMBL18540408 0.84 HSD17B1 (0.40) HSD17B1HSD17B2KDM1AHPGDSCYP3A4
SCHEMBL17426511 0.84 IDO1 (0.46) HSD17B1HSD17B2IDO1
SCHEMBL17426513 0.84 SCN9A (0.42) HSD17B1HSD17B2KDM1AHPGDSCYP3A4
SCHEMBL29505097 0.82 LDHA (0.48) HPGDSCYP3A4IDO1TDO2LDHA
SCHEMBL17780846 0.82 LDHA (0.48) HPGDSCYP3A4IDO1TDO2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563898-B2 Iridium-based luminescent compounds having phenylpyridine moieties with organosilicon group, and organic electroluminescence devices using the compounds as color-producing materials LG DISPLAY CO., LTD. (KR) 2009-07-21 US disclosed