Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.59 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | FES | P07332 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31754774 | 0.87 | HSD17B1 (0.43) | HSD17B1HSD17B2TRPV3HPGDSKDM1A | |
| SCHEMBL13765154 | 0.87 | HSD17B1 (0.43) | HSD17B1HSD17B2TRPV3HPGDSKDM1A | |
| SCHEMBL18069588 | 0.84 | CYP3A4 (0.53) | HSD17B1HSD17B2TRPV3KDM1ACYP3A4 | |
| SCHEMBL16405288 | 0.77 | HSD17B1 (0.45) | HSD17B1HSD17B2KDM1ACYP3A4 | |
| SCHEMBL12957239 | 0.77 | HSD17B1 (0.67) | HSD17B1HSD17B2IRAK4MAP4K4HPGDS | |
| SCHEMBL24134487 | 0.77 | HSD17B1 (0.38) | HSD17B1HSD17B2TRPV3HPGDSKDM1A | |
| SCHEMBL17754240 | 0.76 | HPGDS (0.47) | HSD17B1HSD17B2HPGDSCYP3A4 | |
| SCHEMBL4402515 | 0.76 | HSD17B1 (0.61) | HSD17B1HSD17B2MAP4K4KDM1ACYP3A4 | |
| SCHEMBL26548178 | 0.76 | CYP11B1 (0.45) | HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL12973163 | 0.76 | HSD17B1 (0.59) | HSD17B1HSD17B2MAP4K4KDM1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078330-B2 | Highly branched dendrimers | ISIS INNOVATION LIMITED (GB) | 2015-07-07 | — | — | US | disclosed |
| US-20080211391-A1 | Highly Branched Dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080211391-A1 | Highly Branched Dendrimers | ITGB1, PICALM, BTN3A1 | HSD17B1 829/4885HSD17B2 1602/4885IRAK4 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.