Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790082 | 1.00 | ELANE (0.41) | ELANEPLA2G1BATG4BMAPTTP53 | |
| SCHEMBL24307918 | 0.86 | PLA2G1B (0.39) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL9594137 | 0.86 | ALDH1A1 (0.40) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL13765053 | 0.83 | ALDH1A1 (0.45) | MAPTALDH1A1KMT2AATMCYP1A2 | |
| SCHEMBL29850460 | 0.82 | LMNA (0.39) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL10851634 | 0.82 | LMNA (0.39) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL17093931 | 0.82 | LMNA (0.39) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL13765185 | 0.82 | ELANE (0.46) | ELANEPLA2G1BATG4BMAPTTP53 | |
| SCHEMBL13764941 | 0.82 | LMNA (0.39) | PLA2G1BATG4BMAPTALDH1A1PTPRC | |
| SCHEMBL29850667 | 0.81 | SMN1; SMN2 (0.44) | MAPTALDH1A1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231137-B1 | METHOD OF MODULATING MEMBRANE POTENTIAL OF A CELL | VERSITECH LTD (CN) | 2017-01-25 | — | — | EP | disclosed |
| WO-2009089680-A1 | METHOD OF MODULATING MEMBRANE POTENTIAL OF A CELL | YANG DAN (CN) | 2009-07-23 | — | — | WO | disclosed |