Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355696 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9LMNAGAA | |
| SCHEMBL9915511 | 0.84 | RAB9A (0.44) | ELANEALDH1A1CYP2C9LMNAGAA | |
| SCHEMBL23440237 | 0.84 | TP53 (0.53) | ALDH1A1LMNATP53KDM4EMAPK1 | |
| SCHEMBL13790082 | 0.82 | ELANE (0.41) | ELANEALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL13765035 | 0.82 | ALDH1A1 (0.43) | ELANEALDH1A1LMNAGAAPLA2G1B | |
| SCHEMBL13765196 | 0.82 | ELANE (0.41) | ELANEALDH1A1CYP1A2CYP2C9PLA2G1B | |
| SCHEMBL18262729 | 0.79 | LMNA (0.47) | ALDH1A1CYP1A2CYP2C9LMNAGAA | |
| SCHEMBL13437819 | 0.79 | LMNA (0.47) | ALDH1A1CYP1A2CYP2C9LMNAGAA | |
| SCHEMBL17111877 | 0.79 | LMNA (0.47) | ALDH1A1CYP1A2CYP2C9LMNAGAA | |
| SCHEMBL13765221 | 0.76 | PTPRC (0.40) | ALDH1A1CYP1A2CYP2C9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230301944-A1 | AMINOXY ACID-BASED ANTI-CANCER STEM CELL COMPOUNDS AND METHODS THEREOF | Westlake University (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230301944-A1 | AMINOXY ACID-BASED ANTI-CANCER STEM CELL COMPOUNDS AND METHODS THEREOF | Westlake University (CN) | 2023-09-28 | — | — | US | disclosed |
| WO-2021104199-A1 | AMINOXY ACID-BASED ANTI-CANCER STEM CELL COMPOUNDS AND METHODS THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2021-06-03 | — | — | WO | disclosed |
| EP-2114870-B1 | SYNTHETIC ION CHANNELS | VERSITECH LTD (CN) | 2019-07-03 | — | — | EP | disclosed |
| US-9610263-B2 | Method of modulating membrane potential of a cell | VERSITECH LIMITED (CN) | 2017-04-04 | — | — | US | disclosed |
| US-9610263-B2 | Method of modulating membrane potential of a cell | VERSITECH LIMITED (CN) | 2017-04-04 | — | — | US | disclosed |
| EP-2231137-B1 | METHOD OF MODULATING MEMBRANE POTENTIAL OF A CELL | VERSITECH LTD (CN) | 2017-01-25 | — | — | EP | disclosed |
| US-9162977-B2 | Synthetic ion channels | THE UNIVERSITY OF HONG KONG (CN) | 2015-10-20 | — | — | US | disclosed |
| US-9162977-B2 | Synthetic ion channels | THE UNIVERSITY OF HONG KONG (CN) | 2015-10-20 | — | — | US | disclosed |
| US-20130244944-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2013-09-19 | — | — | US | disclosed |
| US-20130244944-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2013-09-19 | — | — | US | disclosed |
| US-8378138-B2 | self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. | The University of Hong Kong & Versitech Limited (CN) | 2013-02-19 | — | — | US | disclosed |
| US-8378138-B2 | self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. | The University of Hong Kong & Versitech Limited (CN) | 2013-02-19 | — | — | US | disclosed |
| WO-2009089680-A1 | METHOD OF MODULATING MEMBRANE POTENTIAL OF A CELL | YANG DAN (CN) | 2009-07-23 | — | — | WO | disclosed |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2009-06-25 | — | — | US | disclosed |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2009-06-25 | — | — | US | disclosed |
| WO-2008074227-A1 | SYNTHETIC ION CHANNELS | VERSITECH LIMITED (CN) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146513-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2008-06-19 | — | — | US | disclosed |
| US-20080146513-A1 | Synthetic Ion Channels | VERSITECH LIMITED (CN) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244944-A1 | Synthetic Ion Channels | KCNJ2, KCNJ1, KCNN2 | ELANE 3617/4885ALDH1A1 4525/4885CYP1A2 4804/4885 |
| US-20080146513-A1 | Synthetic Ion Channels | KCNJ2, KCNJ1, KCNN2 | ELANE 3617/4885ALDH1A1 4525/4885CYP1A2 4804/4885 |
| US-20230301944-A1 | AMINOXY ACID-BASED ANTI-CANCER STEM CELL COMPOUNDS AND METHODS THEREOF | ABAT, GLS2, ALDH7A1 | ELANE 4188/4885ALDH1A1 120/4885CYP1A2 965/4885 |
| US-20090163595-A1 | Method of Modulating Membrane Potential of a Cell | VDAC1, ATP2A3, ATP2A2 | ELANE 2075/4885ALDH1A1 3766/4885CYP1A2 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.