Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13362364 | 0.83 | HDAC8 (0.56) | HDAC8HDAC6HDAC1PYCR1THRA | |
| SCHEMBL26267232 | 0.81 | HDAC1 (0.59) | HDAC8HDAC6HDAC1PYCR1ALDH1A1 | |
| SCHEMBL609570 | 0.80 | HDAC1 (0.53) | HDAC8HDAC6HDAC1MAPTSMN1; SMN2 | |
| SCHEMBL607930 | 0.78 | HRH3 (0.54) | HDAC6PYCR1ALDH1A1POLBMAPT | |
| SCHEMBL819942 | 0.77 | HDAC1 (0.52) | HDAC8HDAC6HDAC1PYCR1MAPT | |
| SCHEMBL2483550 | 0.75 | HDAC1 (0.55) | HDAC8HDAC6HDAC1ALDH1A1ESR1 | |
| SCHEMBL608835 | 0.74 | PYCR1 (0.35) | HDAC8HDAC6HDAC1PYCR1THRA | |
| SCHEMBL608633 | 0.74 | HRH3 (0.57) | HDAC8HDAC6PYCR1POLBHRH3 | |
| SCHEMBL611049 | 0.74 | PYCR1 (0.46) | HDAC8HDAC6PYCR1ALDH1A1POLB | |
| SCHEMBL4669161 | 0.74 | PTGS1 (0.46) | ALDH1A1SMN1; SMN2KMT2AMEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563387-B2 | Comprising water-soluble salt of synthetic helical polymer having no asymmetric carbon atom as main component of main chain thereof, for example, a polyacetylene derivative having such constitution; provides an unprecedented liquid crystal material or electronic or optically functional polymer material | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-07-21 | — | — | US | disclosed |
| US-20070145329-A1 | Hydrophilic stiff main chain type liquid crystalline composition and chiral sensor utilizing the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-06-28 | — | — | US | disclosed |