SCHEMBL607930

SCHEMBL607930

C=C(C)c1ccc(CN(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.54
NOS1 P29475 2/20 0.48
NOS3 P29474 1/20 0.48
NOS2 P35228 1/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
TAAR1 Q96RJ0 2/20 0.47
LSS P48449 2/20 0.41
PYCR1 P32322 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MCHR1 Q99705 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26345944 0.81 HRH3 (0.52) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL608633 0.79 HRH3 (0.57) HRH3PYCR1POLBHDAC6
SCHEMBL608233 0.79 HRH3 (0.57) HRH3TAAR1MCHR1
SCHEMBL608835 0.79 PYCR1 (0.35) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL12734915 0.78 PYCR1 (0.62) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL659509 0.78 HRH3 (0.82) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL610268 0.78 ALDH1A1 (0.59) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL22651931 0.78 HRH3 (0.48) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL21764563 0.78 HRH3 (0.48) HRH3NOS1NOS3NOS2ALDH1A1
SCHEMBL13765286 0.78 HDAC8 (0.57) HRH3ALDH1A1PYCR1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3661941-B1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2022-12-14 EP disclosed
WO-2021136223-A1 FUSION PROTEINS OF GLP-1 AND GDF15 AND CONJUGATES THEREOF BEIJING QL BIOPHARMACEUTICAL CO., LTD. (CN) 2021-07-08 WO disclosed
EP-3239183-B1 MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER SUMITOMO CHEMICAL CO (JP) 2020-03-11 EP disclosed
US-10118973-B2 Modified conjugated diene polymer, and polymer composition containing said polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-06 US disclosed
CN-104045769-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-10-30 CN disclosed
CN-107001491-B Modified conjugated diene polymer and the polymer composition containing the polymer 住友化学株式会社 2018-07-06 CN disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
CN-104098744-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-02-16 CN disclosed
CN-104045768-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-02-16 CN disclosed
US-20170369599-A1 MODIFIED CONJUGATED DIENE POLYMER, AND POLYMER COMPOSITION CONTAINING SAID POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-12-28 US disclosed
US-20110275756-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-10 US disclosed
WO-2010116063-A1 ETHYLENE COPOLYMER WITH PEG, CATIONIC AND ANIONIC UNITS, COSMETIC COMPOSITION INCLUDING SAME AND TREATMENT METHOD L'OREAL (FR) 2010-10-14 WO disclosed
EP-2174994-A1 Ink jet ink, ink jet recording method, and ink cartridge CANON KABUSHIKI KAISHA (JP) 2010-04-14 EP disclosed
US-20100086686-A1 INK JET INK, INK JET RECORDING METHOD, AND INK CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-08 US disclosed
US-20100086686-A1 INK JET INK, INK JET RECORDING METHOD, AND INK CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-08 US disclosed
EP-2165829-A1 Lithographic printing plate precursor and plate making method thereof Fujifilm Corporation (JP) 2010-03-24 EP disclosed
US-20100062375-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-03-11 US disclosed
EP-0972805-B1 Polyimide-based composite, electronic parts using the composite, and polyimide-based aqueous dispersion JSR CORP (JP) 2004-11-17 EP disclosed
US-6214923-B1 POLYIMIDE COMPONENT AND OTHER POLYMER IN THE SAME PARTICLE IN DISPERSION TO IMPROVE STORAGE STABILITY; IN COMPOSITE, POLYIMIDE FORMS CONTINUOUS PHASE AND POLYMER DISCONTINUOUS PHASE, LOW ELASTIC MODULUS; HEAT RESISTANCE JSR CORPORATION (JP) 2001-04-10 US disclosed
EP-0972805-A2 Polyimide-based composite, electronic parts using the composite, and polyimide-based aqueous dispersion JSR Corporation (JP) 2000-01-19 EP disclosed