Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444800 | 0.98 | MEN1 (0.34) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13880298 | 0.94 | MEN1 (0.33) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19221683 | 0.94 | MEN1 (0.32) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13766307 | 0.93 | ALDH1A1 (0.32) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10106920 | 0.93 | ESR1 (0.34) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8927716 | 0.92 | MEN1 (0.32) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14267918 | 0.91 | CYP1A2 (0.39) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14267914 | 0.91 | MEN1 (0.34) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14444798 | 0.89 | DRD2 (0.35) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL13766142 | 0.89 | PIN1 (0.31) | ALOX5NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622888-B1 | BENZO-, NAPHTHO- AND PHENANTHROCHROMENES SUBSTITUTED WITH AN ARYLAMINE GROUP WITH PHOTOCHROMIC PROPERTIES | CORNING INC (US) | 2009-07-08 | — | — | EP | disclosed |