Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202573 | 0.84 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL301933 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL10338964 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL29437308 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL1150551 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL124981 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL28613032 | 0.79 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL249952 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL69613 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL883715 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042944-A1 | COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE | Luminescence Technology Corp. (TW) | 2016-07-13 | — | — | EP | disclosed |
| EP-2241564-B1 | 3,8-DIAMINOTETRAHYDROQUINOLINE DERIVATIVE | ZERIA PHARM CO LTD (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-1601671-B1 | CYCLOALKYL DERIVATIVES COMPRISING BIOISOSTERIC CARBOXYLIC ACID GROUPS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS A MEDICAMENT | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-29 | — | — | EP | disclosed |