Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10338964 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL10651374 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL30956253 | 0.88 | HSD17B10 (0.62) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL13777208 | 0.88 | HSD17B10 (0.62) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL1246296 | 0.88 | HSPA5 (0.59) | ALDH1A1TSHRHPGDARHTT | |
| SCHEMBL4692660 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL4690719 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL10569740 | 0.88 | ALDH1A1 (0.79) | ALDH1A1TSHRHPGDARHSD17B10 | |
| SCHEMBL3202573 | 0.88 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHSD17B10HTT | |
| SCHEMBL40607 | 0.87 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDARHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 959 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606906-B1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2023-12-27 | — | — | EP | claimed |
| US-11512046-B2 | Heterogeneous catalysts for the direct carbonylation of nitro aromatic compounds to isocyanates | BASF SE | 2022-11-29 | — | — | US | claimed |
| CN-110719905-B | Heterogeneous catalyst for the direct carbonylation of nitroaromatics to isocyanates | 巴斯夫欧洲公司 | 2022-10-28 | — | — | CN | claimed |
| US-20210002210-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2021-01-07 | — | — | US | claimed |
| US-20200246471-A1 | POLYMER DERIVATIVES HAVING PARTICULAR ATOM ARRANGEMENTS | NEKTAR THERAPEUTICS (US) | 2020-08-06 | — | — | US | claimed |
| EP-3606906-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2020-02-12 | — | — | EP | claimed |
| CN-110719905-A | Heterogeneous catalyst for the direct carbonylation of nitroaromatics to isocyanates | 巴斯夫欧洲公司 | 2020-01-21 | — | — | CN | claimed |
| WO-2018185168-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2018-10-11 | — | — | WO | claimed |
| US-9714560-B2 | Protected scale inhibitors and methods relating thereto | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-07-25 | — | — | US | claimed |
| US-9493469-B2 | Piperidine inhibitors of Janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | claimed |
| WO-2005000360-A2 | PEG DERIVATIVES HAVING AN AMIDOCARBONATE LINKAGE | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-01-06 | — | — | WO | claimed |
| WO-2004020400-A1 | ENZYME ACTIVATED SELF-IMMOLATIVE N-SUBSTITUTED NITROGEN MUSTARD PRODRUGS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| EP-0700378-B1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 2000-12-20 | — | — | EP | claimed |
| US-5616600-A | Griseolic acid compounds and their use as a phosphodiesterase inhibitor | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | claimed |
| EP-0700378-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-03-13 | — | — | EP | claimed |
| EP-0700378-A4 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | UNIV CALIFORNIA (US) | 1996-01-22 | — | — | EP | claimed |
| US-5405950-A | N4 -substituted cytidines and process for incorporation into an oligonucleotides | AMOCO CORPORATION (US) | 1995-04-11 | — | — | US | claimed |
| US-5374710-A | Compounds which release nitric oxide upon illumination | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-20 | — | — | US | claimed |
| WO-1994027957-A1 | COMPOUNDS WHICH RELEASE NITRIC OXIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-08 | — | — | WO | claimed |
| US-4631150-A | Process for the preparation of penems | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-12-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002210-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | IDH3B, SOD1, IDH3A | ALDH1A1 449/4885TSHR 4461/4885HPGD 1151/4885 |
| US-11512046-B2 | Heterogeneous catalysts for the direct carbonylation of nitro aromatic compounds to isocyanates | IDH3B, SOD1, IDH3A | ALDH1A1 449/4885TSHR 4461/4885HPGD 1151/4885 |
| US-20200246471-A1 | POLYMER DERIVATIVES HAVING PARTICULAR ATOM ARRANGEMENTS | CD44, PIGO, PGLS | ALDH1A1 1192/4885TSHR 4119/4885HPGD 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.