Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951612 | 1.00 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL6158689 | 0.82 | GPR84 (0.61) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL11805598 | 0.81 | GPR84 (0.55) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL6668005 | 0.81 | GPR84 (0.59) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL27640048 | 0.80 | GPR84 (0.54) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5513681 | 0.79 | GPR84 (0.67) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| Vibrindole A SCHEMBL5960513 | 0.79 | GPR84 (0.71) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL255420 | 0.79 | GPR84 (0.71) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL30626309 | 0.79 | GPR84 (0.71) | GPR84FFAR1HTR2AHTR2CHTR2B | |
| SCHEMBL7316265 | 0.79 | GPR84 (0.51) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9333272-B2 | Fibrin binding peptide conjugates for diagnostic and therapeutic applications | BRACCO IMAGING SPA (IT) | 2016-05-10 | — | — | US | disclosed |
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| CN-101111490-A | 4- (1H-indol-3-yl) -pyrimidin-2-ylamine derivatives and their therapeutic use | CYCLACEL LTD (GB) | 2008-01-23 | — | — | CN | disclosed |
| CN-1814596-A | Muscarinic agonists | ARCADIA PHARMACEUTICALS INC (US) | 2006-08-09 | — | — | CN | disclosed |
| CN-1249051-C | Muscarinic agonists | ACADIA PHARM INC (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1439002-A | Muscarinic agonists | ACADIA PHARM INC (US) | 2003-08-27 | — | — | CN | disclosed |