Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296387 | 0.90 | GPR84 (0.53) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL11805598 | 0.85 | GPR84 (0.55) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL4662003 | 0.84 | MEN1 (0.57) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL29951612 | 0.81 | GPR84 (0.61) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL13767828 | 0.81 | GPR84 (0.61) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL7316265 | 0.81 | GPR84 (0.51) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL1333393 | 0.81 | GPR84 (0.51) | GPR84FFAR1CYP2A6IMPDH2HTR2A | |
| SCHEMBL2661863 | 0.78 | MEN1 (0.54) | GPR84FFAR1CYP2A6IMPDH2MAPT | |
| SCHEMBL27981638 | 0.77 | GPR84 (0.77) | GPR84FFAR1IMPDH2HTR2AHTR2C | |
| SCHEMBL29885627 | 0.77 | MAPT (0.65) | GPR84FFAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220280479-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. | 2022-09-08 | — | — | US | disclosed |
| US-11337961-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210046046-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. | 2021-02-18 | — | — | US | disclosed |
| US-10799479-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10441569-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180280347-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2018-10-04 | — | — | US | disclosed |
| US-20180161308-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2018-06-14 | — | — | US | disclosed |
| US-9918965-B2 | Self-emulsifying formulations of DIM-related indoles | BIORESPONSE, L.L.C. (US) | 2018-03-20 | — | — | US | disclosed |
| EP-3280398-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | Bioresponse LLC (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20170014382-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2017-01-19 | — | — | US | disclosed |
| WO-2016164770-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | BIORESPONSE, L.L.C. (US) | 2016-10-13 | — | — | WO | disclosed |
| EP-1093455-B1 | BIS-INDOLE DERIVATIVES AND THEIR USE AS ANTIINFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6589975-B2 | Administering anti-immunogenic and neurogenic inflammatory bis-indole compounds (soritin B, soritin C, soritin D) for treating the condition associated with inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-08 | — | — | US | disclosed |
| US-20030022815-A1 | Synthetic compounds for treatment of inflammation | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-01-30 | — | — | US | disclosed |
| US-6444697-B2 | ADMINISTERING BIS-INDOLE COMPOUNDS AND THEIR DERIVATIVES AS ANTI-IMMUNOGENIC AND NEUROGENIC INFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC INSTUTITION, INC. | 2002-09-03 | — | — | US | disclosed |
| US-20010056112-A1 | Synthetic compounds for treatment of inflammation | WRIGHT AMY E (US) | 2001-12-27 | — | — | US | disclosed |
| US-6323233-B1 | DIINDOLE COMPOUNDS AS ANTIINFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION INC. | 2001-11-27 | — | — | US | disclosed |
| EP-1093455-A1 | BIS-INDOLE DERIVATIVES AND THEIR USE AS ANTIINFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000002857-A9 | BIS-INDOLE DERIVATIVES AND THEIR USE AS ANTIINFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC (US) | 2000-07-20 | — | — | WO | disclosed |
| WO-2000002857-A1 | BIS-INDOLE DERIVATIVES AND THEIR USE AS ANTIINFLAMMATORY AGENTS | HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220280479-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | GPR84 1667/4885FFAR1 829/4885CYP2A6 1245/4885 |
| US-10441569-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | GPR84 1667/4885FFAR1 829/4885CYP2A6 1245/4885 |
| US-20210046046-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | GPR84 1917/4885FFAR1 954/4885CYP2A6 938/4885 |
| US-11337961-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | GPR84 1917/4885FFAR1 954/4885CYP2A6 938/4885 |
| US-20010056112-A1 | Synthetic compounds for treatment of inflammation | IDO1, IDO2, CXCL10 | GPR84 412/4885FFAR1 979/4885CYP2A6 3568/4885 |
| US-20170014382-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | GPR84 1667/4885FFAR1 829/4885CYP2A6 1245/4885 |
| US-20030022815-A1 | Synthetic compounds for treatment of inflammation | IDO1, IDO2, CXCL10 | GPR84 412/4885FFAR1 979/4885CYP2A6 3568/4885 |
| US-10799479-B2 | Self-emulsifying formulations of DIM-related indoles | IDO1, IDO2, CYP8B1 | GPR84 1917/4885FFAR1 954/4885CYP2A6 938/4885 |
| US-20180280347-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | GPR84 1917/4885FFAR1 954/4885CYP2A6 938/4885 |
| US-20180161308-A1 | SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES | IDO1, IDO2, CYP8B1 | GPR84 1667/4885FFAR1 829/4885CYP2A6 1245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.