Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10225536 | 0.82 | PPARD (0.81) | PPARDPPARA | |
| SCHEMBL13767911 | 0.81 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL10226001 | 0.81 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL7016420 | 0.74 | PPARD (0.74) | PPARDPPARA | |
| SCHEMBL13767965 | 0.73 | TDP1 (0.37) | PPARDPPARAESR1TP53TDP1 | |
| SCHEMBL14355015 | 0.72 | PPARD (0.75) | PPARDPPARA | |
| SCHEMBL13680152 | 0.71 | PPARD (0.58) | PPARDPPARAESR1 | |
| SCHEMBL13767992 | 0.70 | PPARD (0.43) | PPARDPPARA | |
| SCHEMBL5404604 | 0.70 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL7019616 | 0.70 | PPARD (0.72) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667964-B1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | EP | disclosed |