Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10224783 | 0.82 | PPARD (0.52) | PPARDPPARA | |
| SCHEMBL13680169 | 0.78 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL10226001 | 0.73 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL13767964 | 0.73 | PPARD (0.55) | TDP1BACE1TP53PPARDPPARA | |
| SCHEMBL13767911 | 0.73 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL14355021 | 0.73 | PPARD (0.49) | PPARDPPARA | |
| SCHEMBL3696342 | 0.72 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL13767992 | 0.70 | PPARD (0.43) | CYP3A4CYP2C9CYP2C19PPARDPPARA | |
| SCHEMBL19618945 | 0.69 | CYP3A4 (0.50) | ALDH1A1MAPTHPGDALOX5PTGS1 | |
| SCHEMBL7022265 | 0.69 | PPARD (0.45) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667964-B1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-22 | — | — | EP | disclosed |