Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768422 | 0.89 | MAPT (0.46) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL1379362 | 0.80 | MAPT (0.65) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL5260554 | 0.80 | MAPT (0.62) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL23833453 | 0.78 | MAPT (0.66) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL5837033 | 0.77 | PTPRC (0.42) | MAPTHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL3647943 | 0.76 | CFTR (0.40) | MAPTHPGDL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL31564318 | 0.76 | MAPT (0.46) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL1425934 | 0.76 | ADORA1 (0.50) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL13768306 | 0.76 | L3MBTL1 (0.43) | MAPTTDP1TP53HPGDL3MBTL1 | |
| SCHEMBL31564015 | 0.76 | GABRP (0.51) | MAPTTDP1TP53HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |