Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.61 |
| ▸ | MAOA | P21397 | 7/20 | 0.61 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.61 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370634 | 0.88 | HDAC8 (0.73) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL4156354 | 0.86 | HDAC8 (0.60) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL3869317 | 0.84 | HDAC8 (0.60) | HDAC8CTSLCTSBCTSSCTSK | |
| SCHEMBL13768102 | 0.84 | LMNA (0.64) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL4163972 | 0.84 | TACR1 (0.64) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL10709392 | 0.84 | TACR1 (0.60) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL3583048 | 0.83 | MGLL (0.72) | — | |
| SCHEMBL18444606 | 0.80 | KDM1A (0.68) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL4155113 | 0.80 | KDM1A (0.68) | KDM1AMAOARCOR1KDM1BHDAC8 | |
| SCHEMBL7038484 | 0.80 | HDAC8 (0.78) | KDM1AMAOARCOR1KDM1BHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080631-A2 | CHEMO-ENZYMATIC SYNTHESIS OF A C-TERMINAL ARYL AMIDE OF AN AMINO ACID OR PEPTIDE | DSM IP ASSETS BV (NL) | 2009-07-02 | — | — | WO | disclosed |