Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.35 |
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 5/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768826 | 0.78 | — | — | |
| SCHEMBL3762688 | 0.77 | PGR (0.40) | CYP19A1ARSHBGALDH1A1LMNA | |
| SCHEMBL3773101 | 0.74 | PGR (0.39) | CYP19A1ARSHBGLMNACYP3A4 | |
| SCHEMBL13796033 | 0.73 | CYP19A1 (0.35) | CYP19A1ARSHBGLMNACYP3A4 | |
| SCHEMBL8769115 | 0.70 | PGR (0.52) | CYP19A1ARSHBGALDH1A1THRB | |
| SCHEMBL13797594 | 0.70 | CYP19A1 (0.39) | CYP19A1ARSHBGSERPINA6SLC22A1 | |
| SCHEMBL13556656 | 0.70 | SHBG (0.44) | CYP19A1ARSHBGSERPINA6SLC22A1 | |
| SCHEMBL16564466 | 0.70 | PGR (0.41) | CYP19A1ARALDH1A1LMNACYP3A4 | |
| SCHEMBL924267 | 0.68 | PGR (0.40) | CYP19A1ARSHBGALDH1A1LMNA | |
| SCHEMBL924555 | 0.68 | PGR (0.40) | CYP19A1ARSHBGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083272-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15α,16α-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |