Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76393 | 0.81 | ALDH1A1 (0.74) | ALDH1A1CYP19A1KDM4ECA12CA1 | |
| SCHEMBL15842536 | 0.78 | CYP19A1 (0.59) | ALDH1A1CYP19A1KDM4ECA12CA1 | |
| SCHEMBL14506709 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4ECA12CA9AKR1B1 | |
| SCHEMBL17731844 | 0.76 | ALDH1A1 (0.74) | ALDH1A1CYP19A1KDM4EHPGDHSD17B10 | |
| SCHEMBL13769124 | 0.74 | PGR (0.50) | ALDH1A1CYP19A1KDM4ECA12CA1 | |
| SCHEMBL29412607 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ECA12CA1CA9 | |
| SCHEMBL194842 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ECA12CA1CA9 | |
| SCHEMBL13769545 | 0.72 | PGR (0.68) | ALDH1A1KDM4EPGRADORA3MAOB | |
| SCHEMBL13769121 | 0.72 | PGR (0.68) | ALDH1A1KDM4EPGRADORA3MAOB | |
| SCHEMBL15842614 | 0.71 | PGR (0.67) | ALDH1A1KDM4ECA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709699-B1 | CONJUGATED POLYMERS, REPRESENTATION THEREOF, AND USE OF THE SAME | MERCK PATENT GMBH (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |