Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | CA12 | O43570 | 8/20 | 0.59 |
| ▸ | CA9 | Q16790 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | CA1 | P00915 | 6/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | GLA | P06280 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 5/20 | 0.58 |
| ▸ | CA7 | P43166 | 5/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194842 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL29412607 | 0.85 | ALDH1A1 (1.00) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL13769005 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL14802647 | 0.80 | GBA1 (0.65) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL5114392 | 0.80 | ALDH1A1 (0.54) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL13768990 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL15842536 | 0.80 | CYP19A1 (0.59) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL14506709 | 0.79 | ALDH1A1 (0.62) | ALDH1A1CA12CA9KDM4EMCL1 | |
| SCHEMBL8036025 | 0.78 | ALDH1A1 (0.62) | ALDH1A1CA12CA9KDM4ECA1 | |
| SCHEMBL28918555 | 0.77 | ALDH1A1 (0.83) | ALDH1A1CA12CA9KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 908 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250302678-A1 | ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS | PROCTER & GAMBLE (US) | 2025-10-02 | — | — | US | claimed |
| US-20250304727-A1 | PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, COUMARIN-BASED SENSITIZERS AND AMINE ADDITIVES | IGM GROUP B.V. (NL) | 2025-10-02 | — | — | US | claimed |
| US-12350136-B2 | Absorbent articles including perfume and cyclodextrins | THE PROCTER & GAMBLE COMPANY (US) | 2025-07-08 | — | — | US | claimed |
| CN-119954761-A | Method for synthesizing 4-aldehyde-7-methylcoumarin by microwave-assisted method | 齐齐哈尔大学 | 2025-05-09 | — | — | CN | claimed |
| CN-119708027-A | Method for preparing boronated carbonyl derivative | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| EP-4519376-A1 | PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, COUMARIN-BASED SENSITIZERS AND AMINE ADDITIVES | IGM Group B.V. (NL) | 2025-03-12 | — | — | EP | claimed |
| CN-119137224-A | Photoinitiator package comprising a phosphine oxide photoinitiator, a coumarin-based sensitizer and an amine additive | IGM集团公司 | 2024-12-13 | — | — | CN | claimed |
| CN-116272897-B | Magnetic nanoparticle for enriching coumarin compounds as well as preparation method and application thereof | 中国检验检疫科学研究院 | 2024-08-27 | — | — | CN | claimed |
| EP-4356894-A1 | SUSTAINABLE PRODUCT WITH MALODORS | Beiersdorf AG (DE) | 2024-04-24 | — | — | EP | claimed |
| CN-114751896-B | Fluorescent compound containing 7-methylcoumarin structural group | 南昌大学 | 2024-03-29 | — | — | CN | claimed |
| CN-101258140-A | Benzo (B) cycloprop (D) pyran-2-(1H)-one derivatives | FLEXITRAL INC (US) | 2008-09-03 | — | — | CN | claimed |
| EP-1871756-A1 | BENZO (B) CYCLOPROP (D) PYRAN-2-(1H)-ONE DERIVATIVES | Flexitral, Inc. (US) | 2008-01-02 | — | — | EP | claimed |
| US-20060251786-A1 | Cyclopropanated coumarin derivatives | FLEXITRAL, INC | 2006-11-09 | — | — | US | claimed |
| WO-2006111740-A1 | BENZO (B) CYCLOPROP (D) PYRAN-2-(1H)-ONE DERIVATIVES | FLEXITRAL INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-6953853-B2 | Phospholipase inhbitors; antiinflammatory agents; respiratory system disorders | ALTANA PHARMA AG (DE) | 2005-10-11 | — | — | US | claimed |
| US-20040067946-A1 | Phthalatyinone-piperidino-derivatives as pde4 inhibitors | TAKEDA GMBH (DE) | 2004-04-08 | — | — | US | claimed |
| EP-1362044-A1 | PHTHALAZINONE-PIPERIDINO-DERIVATIVES AS PDE4 INHIBITORS | ALTANA Pharma AG (DE) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064584-A1 | PHTHALAYINONE-PIPERIDINO-DERIVATIVES AS PDE4 INHIBITORS | ALTANA PHARMA AG (DE) | 2002-08-22 | — | — | WO | claimed |
| US-5639893-A | Process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | claimed |
| EP-0757989-A1 | A process for producing octahydrocoumarins and same as a product of such process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067946-A1 | Phthalatyinone-piperidino-derivatives as pde4 inhibitors | PDE4A, PDE4B, PDE5A | ALDH1A1 376/4885CA12 3974/4885CA9 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.