Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.48 |
| ▸ | AR | P10275 | 5/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942711 | 0.84 | PGR (0.47) | PGRARNR3C2CYP19A1 | |
| SCHEMBL15417487 | 0.83 | AR (0.56) | PGRARNR3C2CYP19A1MEN1 | |
| SCHEMBL12998934 | 0.83 | PGR (0.64) | PGRARNR3C2CYP19A1MEN1 | |
| SCHEMBL12942855 | 0.76 | PGR (0.60) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL15417445 | 0.76 | AR (0.55) | PGRARNR3C2CYP19A1 | |
| SCHEMBL16715968 | 0.75 | AR (0.82) | PGRARNR3C2 | |
| SCHEMBL12924010 | 0.74 | AR (0.84) | PGRARNR3C2 | |
| SCHEMBL16572788 | 0.74 | PGR (0.41) | PGRARNR3C2CYP19A1 | |
| SCHEMBL12998927 | 0.73 | PGR (0.77) | PGRARNR3C2CYP19A1MEN1 | |
| SCHEMBL13769000 | 0.73 | PGR (0.77) | PGRARNR3C2CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083270-A1 | 15,16-METHYLENE-STEROID-17,17-LACTOL DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |