Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR3A | P46098 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380282 | 0.89 | HTR6 (0.56) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL1378251 | 0.85 | HTR6 (0.52) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL1380036 | 0.83 | HTR6 (0.56) | HTR6NCF1HTR1AHTR3ACYP1A2 | |
| SCHEMBL1377664 | 0.80 | HTR6 (0.53) | HTR6NCF1HTR1AHTR3ACYP1A2 | |
| SCHEMBL1377314 | 0.80 | HTR6 (0.50) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL1374538 | 0.80 | HTR6 (0.50) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL1376935 | 0.79 | HTR6 (0.49) | HTR6NCF1HTR1AHTR3ACYP1A2 | |
| SCHEMBL1378745 | 0.78 | HTR6 (0.56) | HTR6ADRB1NCF1HTR1AHTR3A | |
| SCHEMBL1377014 | 0.76 | HTR6 (0.51) | HTR6ADRB1 | |
| SCHEMBL4311875 | 0.76 | HTR6 (0.50) | HTR6NCF1HTR1AHTR3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |