Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 6/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609974 | 0.92 | MEN1 (0.43) | KMT2AMEN1ALDH1A1GAAPDE4A | |
| SCHEMBL12713205 | 0.88 | ALDH1A1 (0.34) | LTC4SKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL1610550 | 0.86 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL1609999 | 0.85 | ALOX5 (0.34) | ALDH1A1PDE4ACYP2D6SLC6A2SLC6A3 | |
| SCHEMBL1609969 | 0.83 | CHRM3 (0.38) | ALDH1A1PDE4APDE10APDE4DCHRM3 | |
| SCHEMBL1610486 | 0.81 | SMN1; SMN2 (0.34) | LTC4SKMT2AMEN1ALDH1A1SLC6A4 | |
| SCHEMBL1609106 | 0.80 | TRPM8 (0.37) | KMT2AMEN1ALDH1A1GAAPDE4A | |
| SCHEMBL1609271 | 0.79 | KLKB1 (0.34) | KMT2AALDH1A1PDE10APDE4DPDE4B | |
| SCHEMBL13769408 | 0.77 | PDE10A (0.44) | ALDH1A1PDE4APDE10APDE4DCYP2D6 | |
| SCHEMBL12738212 | 0.77 | MEN1 (0.46) | KMT2AMEN1ALDH1A1GAAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |