Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.39 |
| ▸ | ACACA | Q13085 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720005 | 0.89 | MTNR1A (0.38) | MEN1NPC1HTTRAB9AKMT2A | |
| SCHEMBL3666516 | 0.81 | EPHX2 (0.41) | DRD2EPHX2MEN1NPC1HTT | |
| SCHEMBL29923181 | 0.78 | HTR1A (0.40) | ACACBACACADRD2EPHX2MEN1 | |
| SCHEMBL29923228 | 0.78 | HTR1A (0.40) | ACACBACACADRD2EPHX2MEN1 | |
| SCHEMBL29923119 | 0.78 | HTR1A (0.40) | ACACBACACADRD2EPHX2MEN1 | |
| SCHEMBL27214605 | 0.78 | HTR1A (0.40) | ACACBACACADRD2EPHX2MEN1 | |
| SCHEMBL29923116 | 0.78 | HTR1A (0.40) | ACACBACACADRD2EPHX2MEN1 | |
| SCHEMBL19817054 | 0.77 | GAA (0.40) | ACACBACACADRD2EPHX2 | |
| SCHEMBL29866024 | 0.77 | GAA (0.40) | ACACBACACADRD2EPHX2 | |
| SCHEMBL13734927 | 0.77 | ADRA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086139-A1 | CONDENSED PENTACYCLIC DERIVATIVES FOR USE IN THE TREATMENT OF FLAVIVIRIDAE INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2009-07-09 | — | — | WO | disclosed |